How to optimise your health

Understand your genetic risks and be proactive about your health.

Genetic counselling can help you navigate the complexities of consumer genetic tests and guide you to the most appropriate clinical test in addition to helping you implement changes in your life. Before and after the testing.

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Well-known cancer syndromes that can be inherited and confer increased risk of cancers

  • Hereditary breast and ovarian cancer syndrome:
  • Genes: BRCA1 or BRCA2.
  • Cancers: Breast, ovarian, pancreatic, prostate, melanoma
  • Women and men with BRCA1 or BRCA2 genetic mutations have a significantly higher risk of developing breast and other cancers than those without the mutations. Other cancers associated with the BRCA1 and BRCA2 genes include ovarian, pancreatic, prostate, and melanoma.
  • Mismatch repair genes that cause Lynch syndrome. This is a hereditary disorder caused by mutations in the mismatch repair genes MLH1, MSH2, MSH6, PMS2, and EPCAM. People born with mutations in these genes have a significantly higher risk of developing colon, endometrial, and other cancers such as stomach, pancreas, urinary tract, or brain.
  • CDH1. Mutations in the CDH1 gene are associated with hereditary diffuse gastric cancer, a rare type of stomach cancer, as well as breast cancer.
  • PALB2. Inherited mutations in the PALB2 gene are associated with an increased risk of breast cancer. Sometimes, this mutation can also be found in families with multiple cases of pancreatic cancer.
  • STK11. A mutation in the STK11 gene causes Peutz-Jeghers syndrome. People with this condition have a higher-than-average risk of developing cancers of the breast, cervix, ovary, gastrointestinal tract, and pancreas.
  • PTEN. Mutations in the PTEN gene have been linked to an increased risk of breast, head and neck squamous cell carcinoma, lung, and prostate cancers.


Frequently asked questions

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